Nicotinamide
CAS Number: 98-92-0
Chemical Formula: C6H6N2O
Synonyms:
Nicotinamide For Biochemistry
Nicotinamide B.P., U.S.P.
NIACINAMIDE USP GRANULAR
Appearance: White Powder
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Nicotinamide, also known as Vitamin B3 (niacinamide, nicotinic acid amide), is the amide form of nicotinic acid (pyridine-3-carboxylic acid). It is a water‑soluble vitamin that the body does not store. Dietary sources of this vitamin include nicotinamide, nicotinic acid, and tryptophan. Major natural sources of niacin include meat, liver, green leafy vegetables, wheat, oat, palm kernel oil, legumes, yeast, mushrooms, nuts, milk, fish, tea, and coffee.
Parameters
| Property | Value |
| Melting point | 128-131 °C(lit.) |
| Boiling point | 150-160 °C |
| bulk density | 360kg/m3 |
| density | 1.40 |
| vapor density | 4.22 (vs air) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.4660 (estimate) |
| Fp | 182 °C |
| storage temp. | 2-8°C |
| solubility | 691g/l |
| pka | 3.3(at 20℃) |
| form | powder |
| color | white |
| Odor | Odorless |
| PH | 6.0-7.5 (50g/l, H2O, 20℃) |
| PH Range | 9 |
| biological source | synthetic (organic) |
| Water Solubility | 1000 g/L (20 ºC) |
| Decomposition | >=200 °C |
| Merck | 14,6523 |
| BRN | 383619 |
| BCS Class | 1 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Major Application | cell analysis |
| Cosmetics Ingredients Functions | SMOOTHING |
| Cosmetic Ingredient Review (CIR) | Nicotinamide (98-92-0) |
| InChI | 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9) |
| InChIKey | DFPAKSUCGFBDDF-UHFFFAOYSA-N |
| SMILES | NC(=O)c1cccnc1 |
| LogP | -0.38 at 21℃ |
| CAS DataBase Reference | 98-92-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Niacinamide(98-92-0) |
| EPA Substance Registry System | Nicotinamide (98-92-0) |
Safety Information
| Item | Details |
| Hazard Codes | Xi,T,F |
| Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 |
| Safety Statements | 26-36-37/39-45-36/37-16-7 |
| RIDADR | UN1230 – class 3 – PG 2 – Methanol , solution |
| WGK Germany | 1 |
| RTECS | QS3675000 |
| F | 8 |
| Autoignition Temperature | 480 °C |
| TSCA | TSCA listed |
| HS Code | 29362990 |
| Storage Class | 11 – Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 |
| Hazardous Substances Data | 98-92-0(Hazardous Substances Data) |
| Toxicity | LD50 s.c. in rats: 1.68 g/kg (Brazda, Coulson) |
Product Application
Niacinamide is a nutrient and dietary supplement that serves as an available form of niacin. Nicotinic acid is pyridine-3-carboxylic acid, and nicotinamide is its corresponding amide. It is a highly water‑soluble powder, with approximately 1 gram dissolving in 1 milliliter of water. Unlike niacin, it has a bitter taste that is masked in encapsulated products. It is widely used for fortifying cereals, snack foods, and powdered beverages. In personal care, it acts as a skin stimulant and skin smoother. USP‑grade nicotinamide is used as a food additive, in multivitamin formulations, and as an intermediate in pharmaceutical and cosmetic manufacturing.
Fast delivery time
Inventory: 2–3 working days.
New production: 7–10 working days.
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