4′-Hydroxyacetophenone
CAS Number: 99-93-4
Chemical Formula: C8H8O2
Synonyms: Hydroxyacetophenone para 4-Hydroksyacetofenol 4’-hydroxy-acetophenon
Appearance: Almost white to beige Crystalline Powder
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Pharmaceutical secondary standards used for quality control offer pharmaceutical laboratories and manufacturers a convenient and cost-effective choice instead of preparing internal working standards. ChEBI: A monohydroxyacetophenone with a hydroxy group at the 4′ position.
Chemical Properties
| Item | Specification |
| Melting point | 132-135 °C(lit.) |
| Boiling point | 147-148 °C 3 mm Hg(lit.) |
| density | 1.109 |
| vapor pressure | 0.002Pa at 20℃ |
| refractive index | 1.5577 (estimate) |
| FEMA | 4330 4-HYDROXYACETOPHENONE |
| Fp | 166 °C |
| storage temp. | Store below +30°C. |
| solubility | methanol 0.1 g/mL clear |
| form | Crystalline Powder |
| pka | 8.05(at 25℃) |
| color | Almost white to beige |
| Specific Gravity | 1.109 |
| Odor | at 10.00 % in dipropylene glycol mild sweet hawthorn balsam mimosa |
| Odor Type | floral |
| Water Solubility | 10 g/L (22 ºC) |
| JECFA Number | 2040 |
| BRN | 774355 |
| InChIKey | TXFPEBPIARQUIG-UHFFFAOYSA-N |
| LogP | 1.35 at 25℃ |
| CAS DataBase Reference | 99-93-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetophenone 4′-hydroxy-(99-93-4) |
| EPA Substance Registry System | 4-Hydroxyacetophenone (99-93-4) |
Safety Information
| Item | Specification |
| Hazard Codes | Xn Xi |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 26-36/37-37/39-24/25-22-36 |
| WGK Germany | 3 |
| RTECS | PC4959775 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29145000 |
Product Application
4′-Hydroxyacetophenone acts as a ketone building block in the synthesis of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, which are potential cytotoxic agents through Mannich reactions. p-Hydroxyacetophenone is widely applied in pharmaceutical, cosmetic and industrial sectors. It is a natural plant extract found in stems and leaves of Artemisia annua, roots of Rhododendron and Panax ginseng. It supports relief of yellowish eyes caused by hepatitis and other related conditions.
Supply & Delivery
Fast delivery time
Inventory: 2-3 working days
New production: 7-10 working days
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