PROPARGYLAMINE
CAS Number: 2450-71-7
Chemical Formula: C3H5N
Synonyms: Propargulamine, AURORA KA-2552, 2-propyn-1-amine
Appearance: Yellow Liquid
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Propargylamine (HCCCH2–NH2, free-base formula weight 55.08 g/mol), also referred to as 3-amino-1-propyne, is a toxic liquid with a boiling point of 83°C. Its water-soluble hydrochloride salt has a melting range of 179–182°C. It acts on multiple biological targets including aldehyde dehydrogenase, diamine oxidase (copper-containing amine oxidase), glycine cleavage complex (glycine synthase), and monoamine oxidase (flavin-containing amine oxidase).
Chemical Properties
| Item | Value |
| Boiling point | 84 °C |
| density | 0.86 |
| refractive index | n20/D 1.449(lit.) |
| Fp | 39 °F |
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform, Ethyl Acetate |
| form | Liquid |
| pka | 7.89±0.29(Predicted) |
| color | Clear colorless to yellow |
| Appearance | Colorless volatile liquid |
| Water Solubility | miscible |
| Sensitive | Air Sensitive |
| BRN | 773681 |
| Dielectric constant | 6.65 |
| InChI | 1S/C3H5N/c1-2-3-4/h1H,3-4H2 |
| InChIKey | JKANAVGODYYCQF-UHFFFAOYSA-N |
| SMILES | NCC#C |
| CAS DataBase Reference | 2450-71-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Propargylamine(2450-71-7) |
| EPA Substance Registry System | 2-Propyn-1-amine (2450-71-7) |
Safety Information
| Item | Value |
| Hazard Codes | F,T |
| Risk Statements | 11-22-24-34 |
| Safety Statements | 16-26-33-36/37/39-45-28A |
| RIDADR | UN 1992 3/PG 2 |
| WGK Germany | 3 |
| RTECS | UK5250000 |
| F | 3-8-10-34 |
| TSCA | TSCA listed |
| HazardClass | 3.1 |
| PackingGroup | II |
| HS Code | 29211990 |
| Storage Class | 3 – Flammable liquids |
| Hazard Classifications | Acute Tox. 2 Dermal; Acute Tox. 4 Oral; Eye Dam. 1; Flam. Liq. 2; Skin Corr. 1B |
Product Application
Propargylamine is used in the synthesis of chiral and fluorescent macrocycles via 1,3-dipolar cycloaddition reactions between propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene. It serves as a critical intermediate in pharmaceutical manufacturing.
Supply & Delivery
Fast delivery time
Inventory: 2-3 working days
New production: 7-10 working days
Reviews
There are no reviews yet.