L-Leucine
CAS Number: 61-90-5
Chemical Formula: C6H13NO2
Synonyms: (s)-2-amino-4-methylvaleric acid, 2-amino-4-methyl-valeric acid, 4-methyl-L-norvaline
Appearance: White powder
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
L-leucine is one of the eight essential amino acids and belongs to the aliphatic amino acids among twenty proteinogenic amino acids. L-leucine, L-isoleucine, and L-valine are known as three branched-chain amino acids. L-leucine and D-leucine are enantiomers.
Chemical Properties
| Property | Value |
| Melting point | >300 °C (lit.) |
| alpha | 15.4 º (c=4, 6N HCl) |
| Boiling point | 122-134 °C (Press: 2-3 Torr) |
| bulk density | 300-400 kg/m³ |
| density | 1.293 g/cm³ |
| vapor pressure | <1 hPa (20 °C) |
| refractive index | 1.4630 (estimate) |
| FEMA | 3297 | L-LEUCINE |
| Fp | 145-148 °C |
| storage temp. | 2-8 °C |
| solubility | 1 M HCl: 50 mg/mL |
| form | powder |
| pka | 2.328 (at 25℃) |
| color | White to Off-white |
| Odor | at 100.00 %: odorless |
| PH | 5.5-6.5 (20 g/L, H2O, 20℃) |
| biological source | plant |
| Optical Rotation | [α]20/D +15.5°, c = 2 in 6 M HCl |
| Water Solubility | 22.4 g/L (20 °C) |
| λmax | λ: 260 nm Amax: 0.05; λ: 280 nm Amax: 0.05 |
| JECFA Number | 1423 |
| Sublimation | 145-148 ºC |
| Merck | 14,5451 |
| BRN | 1721722 |
| Stability | Moisture and light sensitive. Incompatible with strong oxidising agents. |
| LogP | 0.80 |
| CAS DataBase Reference | 61-90-5 (CAS DataBase Reference) |
| NIST Chemistry Reference | Leucine (61-90-5) |
| EPA Substance Registry System | L-Leucine (61-90-5) |
Safety Information
| Item | Value |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | OH2850000 |
| TSCA | Yes |
| HS Code | 29224995 |
| Hazardous Substances Data | 61-90-5 (Hazardous Substances Data) |
Product Application
Amino acid drugs: Used in amino acid infusions and compound amino acid preparations. Applied in the diagnosis and management of pediatric idiopathic hyperglycemia and glucose metabolism disorders, liver diseases with reduced bile secretion, anemia, poisoning, muscular dystrophy, poliomyelitis, neuritis, and mental disorders.
Supply & Delivery
Fast delivery time
Inventory: 2-3 working days
New production: 7-10 working days
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