Acetylsalicylic acid
CAS Number: 50-78-2
Chemical Formula: C9H8O4
Synonyms: ACETYLSALICYLIC ACID BP2000，ASPIRIN，2-Acetoxybenzoic acid
Appearance: White crystalline
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Acetylsalicylic acid belongs to the benzoic acid family, derived from salicylic acid by acetylation of the phenolic hydroxyl group. As a non-steroidal anti-inflammatory drug, it acts as a cyclooxygenase inhibitor. It has long been used for analgesic, antipyretic and anti-inflammatory effects. Recent studies also show that it helps reduce the risk of heart attacks due to its anti-platelet aggregation activity.
Chemical Properties
| Item | Value |
| Melting point | 134-136 °C (lit.) |
| Boiling point | 272.96°C (rough estimate) |
| density | 1.35 |
| refractive index | 1.4500 (estimate) |
| Fp | 250 °C |
| storage temp. | 2-8°C |
| solubility | H2O: 10 mg/mL at 37 °C |
| form | crystalline |
| color | white |
| pka | 3.5(at 25℃) |
| biological source | synthetic |
| Water Solubility | 3.3 g/L (20 ºC) |
| ε(extinction coefficient) | 190 at 298nm in aqueous base at 1mM; 409 at 231nm in aqueous base at 1mM; 466 at 230nm in aqueous acid at 1mM; 68 at 278nm in aqueous acid at 1mM |
| Merck | 14,851 |
| BRN | 779271 |
| Exposure limits | ACGIH: TWA 5 mg/m3; NIOSH: TWA 5 mg/m3 |
| BCS Class | 3 |
| Stability: | Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, iodides, iron salts, quinine salts and other compounds. |
| Cosmetics Ingredients Functions | EXFOLIATING |
| InChIKey | BSYNRYMUTXBXSQ-UHFFFAOYSA-N |
| LogP | 1.190 |
| CAS DataBase Reference | 50-78-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 2-(acetyloxy)-(50-78-2) |
| EPA Substance Registry System | Aspirin (50-78-2) |
Safety Information
| Item | Value |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36/37/39 |
| RIDADR | UN 1851 |
| OEB | B |
| OEL | TWA: 5 mg/m3 |
| WGK Germany | 1 |
| RTECS | VO0700000 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29182210 |
| Hazardous Substances Data | 50-78-2(Hazardous Substances Data) |
| Toxicity | LD50 orally in mice, rats: 1.1, 1.5 g/kg (Hart) |
Product Application
Acetylsalicylic acid serves as a raw material for 4-hydroxycoumarin, an intermediate for rodenticides. It is used in manufacturing outdoor structural components and high-light exposure parts such as automobile bodies, agricultural machinery parts, instruments, lamps and road markings. As one of the earliest and most widely used antipyretic analgesic and anti-rheumatic drugs, it provides fast and effective effects including fever reduction, pain relief, anti-inflammation and anti-platelet aggregation. It is safe with easy diagnosis and treatment in case of overdose and rare allergic reactions. It is commonly used for colds, fever, headache, neuralgia, joint pain, muscle pain, rheumatic fever, acute arthritis, rheumatoid arthritis and toothache. It is listed in the National Essential Medicine List and also used as a pharmaceutical intermediate.
Supply & Delivery
Fast delivery time
Inventory: 2-3 working days
New production: 7-10 working days
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