HARRINGTONINE
CAS Number 26833-85-2
Chemical Formula C28H37NO9
Synonyms
HARRINGTONIN
HARRINGTONINE
2’R-HARRINGTONINE
Appearance White Powder
MOQ (Minimum Order Quantity) 1 FCL (Full Container Load)
Harringtonine is a naturally occurring alkaloid that suppresses protein synthesis at low micromolar levels. It freezes ribosomes right after translation starts. Although harringtonine has been studied for anticancer potential, its analog homoharringtonine shows stronger activity, especially against chronic myelogenous leukemia. The ribosome-stabilizing effect of harringtonine can be used to isolate ribosome-protected mRNA fragments for translation analysis.
HARRINGTONINE Chemical Properties
| Melting point | 73～75℃ |
| Boiling point | 679.4±55.0 °C(Predicted) |
| density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
| pka | 11.62±0.29(Predicted) |
| form | A crystalline solid |
| color | White to light yellow |
Safety Information
| RIDADR | 1544 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
Product Application of HARRINGTONINE CAS#26833-85-2
A natural compound with prominent antitumor effects.
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